We demonstrate phase sensitivity in a horizontally guided, acceleration-sensitive atom interferometer with a momentum separation of 80ℏk between its arms. A fringe visibility of 7% is observed. Our coherent pulse sequence accelerates the cold cloud in an optical waveguide, an inherently scalable route to large momentum separation and high sensitivity. We maintain coherence at high momentum separation due to both the transverse confinement provided by the guide and our use of optical δ-kick cooling on our cold-atom cloud. We also construct a horizontal interferometric gradiometer to measure the longitudinal curvature of our optical waveguide.